AACOCF3 (Arachidonyl trifluoromethyl ketone), Phospholipase-A2 inhibitor (ab120350)
Key features and details
- Phospholipase-A2 inhibitor
- CAS Number: 149301-79-1
- Supplied in ethanol (5 mg/ml)
- Form / State: Liquid
- Source: Synthetic
製品の概要
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製品名
AACOCF3 (Arachidonyl trifluoromethyl ketone), Phospholipase-A2 inhibitor -
製品の詳細
Phospholipase-A2 inhibitor -
別名
- Arachidonyl trifluoromethyl ketone
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生理活性の詳細
Cell-permeable analog of arachidonic acid (ab120916). Widely used as an inhibitor of the 85-kDa cytosolic group IV phospholipase A2 (cPLA2) and calcium-independent group VI phospholipase A2 (iPLA2) (IC50 values are 1.5 and 6.0 μM, respectively) . In non-neural cells, also inhibits cyclooxygenase and acyltransferase activities.
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CAS 番号
149301-79-1 -
構造式
製品の特性
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体系名
(6Z,9Z,12Z,15Z)-1,1,1-Trifluorohenicosa-6,9,12,15-tetraen-2-one -
分子量
356.47 -
分子式
C21H31F3O -
PubChem 登録番号
5280436 -
保存方法
Store at -20°C. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Supplied in ethanol (5 mg/ml) -
使用に関する注意
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
FC(F)(F)C(=O)CCCC=C/C/C=CC/C=CC/C=CCCCCC -
由来
Synthetic
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研究分野
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab120350 は 1 報の論文で使用されています。
- Monson EA et al. Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response. Nat Commun 12:4303 (2021). PubMed: 34262037