Anti-5HT4 Receptor 抗体 (ab113004)

製品の概要

  • 製品名Anti-5HT4 Receptor antibody
    5HT4 Receptor 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 5HT4 Receptor
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 1-30 of Human 5HT4 Receptor (NP_001035259.1, NP_000861.1, NP_001035262.2, NP_955525.1).

  • ポジティブ・コントロール
    • MDA-MB435 cell line and Mouse liver tissue lysates

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab113004 was purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab113004 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 44 kDa.

ターゲット情報

  • 関連性The 5HT4 Receptor is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulates adenylate cyclase. 5HT4a receptors may play a role in opioid-induced respiratory depression.
  • 細胞内局在Cell membrane; Multi-pass membrane protein. Endosome. Note: Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.
  • 参照データベース
  • 別名
    • 5 HT 4 antibody
    • 5 HT4 antibody
    • 5 HT4R antibody
    • 5 hydroxytryptamine 4 receptor antibody
    • 5 hydroxytryptamine receptor 4 antibody
    • 5 hydroxytryptamine serotonin receptor 4 antibody
    • 5 hydroxytryptamine4 receptor antibody
    • 5-HT-4 antibody
    • 5-ht4 antibody
    • 5-HT4R antibody
    • 5H4 antibody
    • 5HT 4 antibody
    • 5HT4 antibody
    • 5ht4 receptor antibody
    • 5HT4R antibody
    • Cardiac 5 HT4 receptor antibody
    • HTR 4 antibody
    • HTR4 antibody
    • serotonin 4 receptor antibody
    • Serotonin 5 HT4 receptor antibody
    • serotonin 5-ht-4 receptor antibody
    • serotonin 5-ht-4a antibody
    • Serotonin receptor 4 antibody
    see all

Anti-5HT4 Receptor antibody 画像

  • Anti-5HT4 Receptor antibody (ab113004) at 1/100 dilution + MDA-MB435 cell line lysate at 35 µg

    Predicted band size : 44 kDa
  • Anti-5HT4 Receptor antibody (ab113004) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 44 kDa

Anti-5HT4 Receptor antibody (ab113004) 使用論文

ab113004 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (SH-SY5Y)
Permeabilization Yes - Triton X-100 (0,25%)
Specification SH-SY5Y
Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 20°C
Fixative Paraformaldehyde
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投稿 Feb 15 2016

Thank you very much for confirming these details and sending the excellent image! The band at a different molecular weight detected in the liver sample (lane 2) may be due to a tissue-specific post-translational modification pattern: According to th...

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Thank you for taking the time to complete our questionnaire and contact us. I am sorry to hear you have had difficulty obtaining satisfactory results from this 5HT4 antibody. Reviewing this case, I would appreciate if you can confirm some further d...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"