製品の概要

  • 製品名Anti-5HT3B receptor antibody
    5HT3B receptor 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to 5HT3B receptor
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee
  • 免疫原

    Synthetic peptide: C-

    SNYLQTQDQTDQQE

    , corresponding to internal sequence amino acids (near C terminus) 389-402 of Human 5HT3B receptor (NP_006019.1).

  • ポジティブ・コントロール
    • Human brain (cerebral cortex, hippocampus and amygdala lysate)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 50 kDa).

ターゲット情報

  • 機能This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
  • 組織特異性Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta.
  • 配列類似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily.
  • 翻訳後修飾N-glycosylation required for membrane localization.
  • 細胞内局在Cell membrane. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5 HT3 B antibody
    • 5 HT3B antibody
    • 5 HTR3B antibody
    • 5 hydroxytryptamine 3 receptor B subunit antibody
    • 5 hydroxytryptamine receptor 3B antibody
    • 5 hydroxytryptamine serotonin receptor 3B antibody
    • 5-HT3-B antibody
    • 5-HT3B antibody
    • 5-hydroxytryptamine receptor 3B antibody
    • 5HT3B_HUMAN antibody
    • 5HTR3B antibody
    • Htr3b antibody
    • Serotonin gated ion channel subunit antibody
    • Serotonin receptor 3B antibody
    see all

Anti-5HT3B receptor antibody 画像

  • Anti-5HT3B receptor antibody (ab90429) at 1 µg/ml + Human cerebral cortex lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 50 kDa
    Observed band size : ~51 kDa (why is the actual band size different from the predicted?)

Anti-5HT3B receptor antibody (ab90429) 使用論文

ab90429 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"