製品の概要

  • 製品名
    Anti-5HT3A receptor antibody
    5HT3A receptor 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to 5HT3A receptor
  • 特異性
    ab51950 is expected to recognise both reported isoforms (NP_998786.1 and NP_000860.1).
  • アプリケーション
    適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human 5HT3A receptor aa 390-401 (internal sequence).
    Sequence:

    CGPQDFEKSPRDR


    Database link: P46098

  • ポジティブ・コントロール
    • Human Colon lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab51950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa). A band of unknown identity is also consistently observed at 200kDa. This band is successfully blocked by incubation with the immunising peptide but we are unsure of it's identity.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 機能
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
  • 組織特異性
    Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.
  • 配列類似性
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3A sub-subfamily.
  • 細胞内局在
    Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5 HT 3 antibody
    • 5 HT3 receptor antibody
    • 5 HT3A antibody
    • 5 HT3A receptor antibody
    • 5 HT3RA antibody
    • 5 hydroxytryptamine (serotonin) receptor 3A antibody
    • 5-HT-3 antibody
    • 5-HT3-A antibody
    • 5-HT3A antibody
    • 5-HT3R antibody
    • 5-hydroxytryptamine receptor 3 antibody
    • 5-hydroxytryptamine receptor 3A antibody
    • 5HT receptor antibody
    • 5HT3 serotonin receptor antibody
    • 5HT3A_HUMAN antibody
    • 5HT3R antibody
    • HTR3 antibody
    • Htr3a antibody
    • Serotonin receptor 3A antibody
    • Serotonin-gated ion channel receptor 3a antibody
    • Serotonin-gated ion channel receptor antibody
    see all

画像

  • Anti-5HT3A receptor antibody (ab51950) at 0.3 µg/ml + 35 µg of Human Colon lysate (in RIPA buffer)

    Predicted band size : 55 kDa
    Observed band size : 55 kDa
    Additional bands at : 200 kDa. We are unsure as to the identity of these extra bands.

参考文献

ab51950 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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