製品の概要

  • 製品名
    Anti-5HT3A receptor antibody
    5HT3A receptor 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to 5HT3A receptor
  • 由来種
    Goat
  • アプリケーション
    適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human 5HT3A receptor aa 390-401 (internal sequence) (Cysteine residue).
    Sequence:

    GPQDFEKSPRDR


    Database link: P46098

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • ポジティブ･コントロール
    • Human Small Intestine tissue; Human Colon lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/128000.
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 55 kDa.
IHC-P Use a concentration of 3.75 µg/ml.

ターゲット情報

  • 機能
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
  • 組織特異性
    Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.
  • 配列類似性
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3A sub-subfamily.
  • 細胞内局在
    Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 参照データベース
    • 別名
      • 5 HT 3 antibody
      • 5 HT3 receptor antibody
      • 5 HT3A antibody
      • 5 HT3A receptor antibody
      • 5 HT3RA antibody
      • 5 hydroxytryptamine (serotonin) receptor 3A antibody
      • 5-HT-3 antibody
      • 5-HT3-A antibody
      • 5-HT3A antibody
      • 5-HT3R antibody
      • 5-hydroxytryptamine receptor 3 antibody
      • 5-hydroxytryptamine receptor 3A antibody
      • 5HT receptor antibody
      • 5HT3 serotonin receptor antibody
      • 5HT3A_HUMAN antibody
      • 5HT3R antibody
      • HTR3 antibody
      • Htr3a antibody
      • Serotonin receptor 3A antibody
      • Serotonin-gated ion channel receptor 3a antibody
      • Serotonin-gated ion channel receptor antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - 5HT3A receptor antibody (ab111983)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - 5HT3A receptor antibody (ab111983)
      ab111983, at 3.75µg/ml, staining 5HT3A receptor in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.
    • Western blot - 5HT3A receptor antibody (ab111983)
      Western blot - 5HT3A receptor antibody (ab111983)
      Anti-5HT3A receptor antibody (ab111983) at 0.3 µg/ml + Human Colon lysate (in RIPA buffer) at 35 µg

      Developed using the ECL technique.

      Predicted band size: 55 kDa

    参考文献

    ab111983 has not yet been referenced specifically in any publications.

    ab111983 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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