Anti-5HT3B receptor 抗体 (ab115023)
Key features and details
- Goat polyclonal to 5HT3B receptor
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-5HT3B receptor antibody
5HT3B receptor 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to 5HT3B receptor -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide:
C-QEDIENDKRSFLND
, corresponding to internal sequence amino acids 187-200 of Rat 5HT3B receptor (NP_071525.1) -
ポジティブ・コントロール
- Rat brain lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab115023 was purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab115023の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa). 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. -
組織特異性
Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta. -
配列類似性
Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily. -
翻訳後修飾
N-glycosylation required for membrane localization. -
細胞内局在
Cell membrane. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. - Information by UniProt
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参照データベース
- Entrez Gene: 58963 Rat
- SwissProt: Q9JJ16 Rat
- Unigene: 87106 Rat
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別名
- 5 HT3 B antibody
- 5 HT3B antibody
- 5 HTR3B antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (1)
ab115023 は 1 報の論文で使用されています。
- Li F et al. Shuyu Capsules Relieve Premenstrual Syndrome Depression by Reducing 5-HT3AR and 5-HT3BR Expression in the Rat Brain. Neural Plast 2016:7950781 (2016). PubMed: 27725889