製品の概要

  • 製品名Anti-58K Golgi protein antibody
    58K Golgi protein 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 58K Golgi protein
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to a sequence within amino acids 1-221 of Human 58K Golgi protein (NP_996848).

  • ポジティブ・コントロール
    • HepG2 whole cell lysate, NCIN87 xenograft tissue.

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab97341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 59 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
    Binds and promotes bundling of vimentin filaments originating from the Golgi.
  • パスウェイAmino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (transferase route): step 1/1.
    One-carbon metabolism; tetrahydrofolate interconversion.
  • 関連疾患Defects in FTCD are the cause of glutamate formiminotransferase deficiency (FIGLU-URIA) [MIM:229100]; also known as formiminoglutamicaciduria (FIGLU-uria). It is an autosomal recessive disorder. Features of a severe phenotype, include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia, and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay, and no hematological abnormalities.
  • 配列類似性In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
    In the N-terminal section; belongs to the formiminotransferase family.
  • 細胞内局在Cytoplasm > cytoskeleton > centrosome > centriole. Golgi apparatus. More abundantly located around the mother centriole.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Formimidoyltetrahydrofolate cyclodeaminase antibody
    • Formimidoyltransferase cyclodeaminase antibody
    • Formiminotetrahydrofolate cyclodeaminase antibody
    • Formiminotransferase cyclodeaminase antibody
    • Formiminotransferase-cyclodeaminase antibody
    • FTCD antibody
    • FTCD_HUMAN antibody
    • Glutamate formiminotransferase antibody
    • Glutamate formyltransferase antibody
    • LCHC 1 antibody
    • LCHC1 antibody
    see all

Anti-58K Golgi protein antibody 画像

  • Anti-58K Golgi protein antibody (ab97341) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 59 kDa
  • Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using ab97341 at 1/100 dilution.

Anti-58K Golgi protein antibody (ab97341) 使用論文

ab97341 has not yet been referenced specifically in any publications.

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