製品の概要

  • 製品名4-Oxo-2-nonenal (4-ONE)
  • 製品の詳細
    Lipid peroxidation product. TRPA1 activator.
  • 別名
    • 4-ONE
  • 生理活性の詳細Lipid peroxidation product, actively modifies histidine and lysine residues on proteins and causes protein cross-linking. Shows a variety of biological activities and is a TRPA1 activator (EC50 = 1.9 µM). Active in vivo.
  • 精製度> 98%

製品の特性

    4-Oxo-2-nonenal (4-ONE) (ab120878) 使用論文

    This product has been referenced in:
    • Näsström T  et al. The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of a-synuclein oligomers with distinct biochemical, morphological, and functional properties. Free Radic Biol Med 50:428-37 (2011). Read more (PubMed: 21130160) »
    • Graepel R  et al. 4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo. J Pharmacol Exp Ther 337:117-24 (2011). Read more (PubMed: 21205926) »
    • Lee SH & Blair IA Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation. Chem Res Toxicol 13:698-702 (2000). Read more (PubMed: 10956056) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120878.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"