Anti-4 Hydroxynonenal 抗体 (ab46544)
Key features and details
- Goat polyclonal to 4 Hydroxynonenal
- Isotype: IgG
製品の概要
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製品名
Anti-4 Hydroxynonenal antibody
4 Hydroxynonenal 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to 4 Hydroxynonenal -
由来種
Goat -
特異性
This antibody specifically binds to HNE modified proteins. -
免疫原
HNE conjugated to KLH
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.435% Sodium chloride, 30% Glycerol -
Concentration information loading...
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特記事項(精製)
Antibody was purified by HNE modified Protein-Sepharose affinity column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
ターゲット情報
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関連性
Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress. -
細胞内局在
Cytoplasmic -
別名
- 4 HNE antibody
- 4-Hydroxy-2-Nonenal antibody
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (30)
ab46544 は 30 報の論文で使用されています。
- Malakul W et al. Novel Coconut Vinegar Attenuates Hepatic and Vascular Oxidative Stress in Rats Fed a High-Cholesterol Diet. Front Nutr 9:835278 (2022). PubMed: 35356733
- Giuliani KTK et al. Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells. Cell Death Dis 13:739 (2022). PubMed: 36030251
- Stoffel W et al. High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis-inactivated Δ6-fatty acid desaturase-deficient mouse. Mol Metab 54:101335 (2021). PubMed: 34530175
- Li Q et al. Novel function of fluvastatin in attenuating oxidized low-density lipoprotein-induced endothelial cell ferroptosis in a glutathione peroxidase4- and cystine-glutamate antiporter-dependent manner. Exp Ther Med 22:1275 (2021). PubMed: 34594412
- Feng H et al. Transferrin Receptor Is a Specific Ferroptosis Marker. Cell Rep 30:3411-3423.e7 (2020). PubMed: 32160546