製品の概要

  • 製品名3-APPA (CGP 27492)
  • 製品の詳細
    Potent, selective GABAB agonist
  • 別名
    • CGP 27492
  • 生理活性の詳細Potent, selective GABAB agonist (IC50 = 5 nM). Partial agonist activity reported.

    Also available in simple stock solutions (ab146708) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度> 98%

製品の特性

    3-APPA (CGP 27492) (ab120329) 使用論文

    This product has been referenced in:
    • Guide to Receptors and Channels (GRAC), 4th Edition. Br J Pharmacol 158 Suppl 1:S1-254 (2009). Read more (PubMed: 19883461) »
    • Hirst WD  et al. Pharmacological characterisation of a cell line expressing GABA B1b and GABA B2 receptor subunits. Biochem Pharmacol 65:1103-13 (2003). Read more (PubMed: 12663046) »
    • Ong J  et al. 3-Aminopropanephosphinic acid is a potent agonist at peripheral and central presynaptic GABAB receptors. Brain Res 526:138-42 (1990). Read more (PubMed: 1964105) »
    • Seabrook GR  et al. Electrophysiological characterization of potent agonists and antagonists at pre- and postsynaptic GABAB receptors on neurones in rat brain slices. Br J Pharmacol 101:949-57 (1990). Read more (PubMed: 1964824) »

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