Anti-14-3-3 zeta 抗体, prediluted (ab32623)

製品の概要

  • 製品名Anti-14-3-3 zeta antibody, prediluted
    14-3-3 zeta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 14-3-3 zeta, prediluted
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    AGDDKKGIVDQSQQAY

    , corresponding to amino acids 134-149 of Human 14-3-3 zeta

  • ポジティブ・コントロール
    • NIH3T3 cells. Breast carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab32623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
WB 1/1.

ターゲット情報

  • 機能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
  • 配列類似性Belongs to the 14-3-3 family.
  • 翻訳後修飾The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53. This phosphorylation appears to be activated by sphingosine. Phosphorylation on Thr-232; inhibits binding of RAF1.
  • 細胞内局在Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 14 3 3 delta antibody
    • 14 3 3 protein zeta/delta antibody
    • 14 3 3 protein/cytosolic phospholipase A2 antibody
    • 14 3 3 zeta antibody
    • 14-3-3 protein zeta/delta antibody
    • 1433Z_HUMAN antibody
    • Epididymis luminal protein 4 antibody
    • Epididymis secretory protein Li 3 antibody
    • HEL S 3 antibody
    • HEL4 antibody
    • KCIP-1 antibody
    • KCIP1 antibody
    • MGC111427 antibody
    • MGC126532 antibody
    • MGC138156 antibody
    • Phospholipase A2 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody
    • Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody
    • YWHAD antibody
    • YWHAZ antibody
    see all

Anti-14-3-3 zeta antibody, prediluted 画像

  • IHC staining of formalin-fixed, paraffin-embedded human breast carcinoma with prediluted ab32623.
  • Anti-14-3-3 zeta antibody (ab32622) at 1/25 dilution + lysate prepared from 293 cells

    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

Anti-14-3-3 zeta antibody, prediluted (ab32623) 使用論文

ab32623 has not yet been referenced specifically in any publications.

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