Anti-14-3-3 zeta 抗体, prediluted (ab32623)

製品の概要

  • 製品名
    Anti-14-3-3 zeta antibody, prediluted
    14-3-3 zeta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 14-3-3 zeta, prediluted
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide. This information is considered to be commercially sensitive.

  • ポジティブ・コントロール
    • NIH3T3 cells. Breast carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab32623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
WB 1/1.

ターゲット情報

  • 機能
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
  • 配列類似性
    Belongs to the 14-3-3 family.
  • 翻訳後修飾
    The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53. This phosphorylation appears to be activated by sphingosine. Phosphorylation on Thr-232; inhibits binding of RAF1.
  • 細胞内局在
    Cytoplasm. Melanosome. Located to stage I to stage IV melanosomes.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 14 3 3 delta antibody
    • 14 3 3 protein zeta/delta antibody
    • 14 3 3 protein/cytosolic phospholipase A2 antibody
    • 14 3 3 zeta antibody
    • 14-3-3 protein zeta/delta antibody
    • 1433Z_HUMAN antibody
    • Epididymis luminal protein 4 antibody
    • Epididymis secretory protein Li 3 antibody
    • HEL S 3 antibody
    • HEL4 antibody
    • KCIP-1 antibody
    • KCIP1 antibody
    • MGC111427 antibody
    • MGC126532 antibody
    • MGC138156 antibody
    • Phospholipase A2 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody
    • Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide antibody
    • YWHAD antibody
    • YWHAZ antibody
    see all

画像

  • IHC staining of formalin-fixed, paraffin-embedded human breast carcinoma with prediluted ab32623.
  • Anti-14-3-3 zeta antibody (ab32622) at 1/25 dilution + lysate prepared from 293 cells

    Observed band size: 30 kDa (why is the actual band size different from the predicted?)



    ab32622 used in the image is the undiluted version of ab32623.

参考文献

ab32623 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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