Anti-14-3-3 Theta + Tau (phospho S232) 抗体 (ab63369)
Key features and details
- Rabbit polyclonal to 14-3-3 Theta + Tau (phospho S232)
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-14-3-3 Theta + Tau (phospho S232) antibody
14-3-3 Theta + Tau 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to 14-3-3 Theta + Tau (phospho S232) -
由来種
Rabbit -
特異性
ab63369 detects 14-3-3 Theta + Tau only when phosphorylated at serine 232.
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アプリケーション
適用あり: ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Synthetic peptide corresponding to Human 14-3-3 Theta + Tau (phospho S232). (S-D-SP-A-G).
Database link: P27348 -
ポジティブ・コントロール
- ICC/IF: HeLa cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab63369の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
1/500 - 1/1000.
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特記事項 |
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ICC/IF
1/500 - 1/1000. |
ターゲット情報
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機能
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. -
組織特異性
Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. -
配列類似性
Belongs to the 14-3-3 family. -
翻訳後修飾
Ser-232 is probably phosphorylated by CK1. -
細胞内局在
Cytoplasm. In neurons, axonally transported to the nerve terminals. - Information by UniProt
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参照データベース
- Entrez Gene: 10971 Human
- Entrez Gene: 100503129 Mouse
- Entrez Gene: 22630 Mouse
- Omim: 609009 Human
- SwissProt: P27348 Human
- SwissProt: P68254 Mouse
- Unigene: 611799 Human
- Unigene: 74405 Human
see all -
別名
- 14-3-3 protein T cell antibody
- 14-3-3 protein T-cell antibody
- 14-3-3 protein tau antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab63369 は 1 報の論文で使用されています。
- McFerrin MB et al. Dysregulation of 14-3-3 proteins in neurodegenerative diseases with Lewy body or Alzheimer pathology. Ann Clin Transl Neurol 4:466-477 (2017). PubMed: 28695147