製品の概要

  • 製品名Anti-14-3-3 Tau antibody
    14-3-3 Tau 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 14-3-3 Tau
  • 特異性Detects endogenous levels of total 14-3-3 Tau protein.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide within Human 14-3-3 Tau (internal sequence). The exact sequence is proprietary.

  • ポジティブ・コントロール
    • WB: HUVEC and HeLa cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab64991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).
ELISA 1/20000.

ターゲット情報

  • 機能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
  • 組織特異性Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.
  • 配列類似性Belongs to the 14-3-3 family.
  • 翻訳後修飾Ser-232 is probably phosphorylated by CK1.
  • 細胞内局在Cytoplasm. In neurons, axonally transported to the nerve terminals.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 14 3 3 protein T cell antibody
    • 14 3 3 protein tau antibody
    • 14 3 3 protein theta antibody
    • 14 3 3 tau antibody
    • 14 3 3 theta antibody
    • 14-3-3 protein T-cell antibody
    • 14-3-3 protein tau antibody
    • 14-3-3 protein theta antibody
    • 1433T_HUMAN antibody
    • 1C5 antibody
    • HS1 antibody
    • KCIP1 antibody
    • Protein HS1 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • Protein tau antibody
    • tyr3/trp5 monooxygenase activation protein, theta antibody
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, theta polypeptide antibody
    • Ywhaq antibody
    see all

Anti-14-3-3 Tau antibody 画像

  • All lanes : Anti-14-3-3 Tau antibody (ab64991) at 1/500 dilution

    Lane 1 : Extracts from HUVEC cells at 5-30ug with no immunizing peptide
    Lane 2 : Extracts from HeLa cells at 5-30ug with no immunizing peptide
    Lane 3 : Extracts from HeLa cells at 5-30ug with immunizing peptide at 5-10ug


    Predicted band size : 28 kDa
    Observed band size : 28 kDa

Anti-14-3-3 Tau antibody (ab64991) 使用論文

ab64991 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Human Tissue lysate - whole (Breast)
Loading amount 20 µg
Specification Breast
Gel Running Conditions Non-reduced Denaturing (12 %)
Blocking step Milk as blocking agent for 16 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
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投稿 Nov 22 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"