製品の概要

  • 製品名Anti-14-3-3 beta + zeta antibody
    14-3-3 beta + zeta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 14-3-3 beta + zeta
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic non-phosphopeptide derived from human 14-3-3 beta + zeta around the phosphorylation site of serine 184/186 (L-N-SP-P-E).

  • ポジティブ・コントロール
    • Extract from 3T3 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab79194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 28 kDa.
ELISA 1/10000.

ターゲット情報

  • 関連性14-3-3 proteins are highly conserved proteins which play a role in both signal transduction and progression through the cell cycle by binding to and regulating several different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms: alpha, beta, gamma, delta, epsilon, zeta, and eta. An eighth subtype, termed theta has been found in rat brain. The 14-3-3 proteins exists in vitro and in vivo as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C. 14-3-3 proteins are localized in the cytoplasm of neurons in the cerebral cortex and are axonally transported to the nerve terminals. They may be present at lower levels in various other eukaryotic tissues. Northern blot analysis has shown expression of the eta chain in cultured cell lines derived from various tumors.
  • 細胞内局在Cytoplasmic. Melanosome (fractions from stage I to stage IV)
  • 参照データベース
  • 別名
    • 14 3 3 protein beta antibody
    • 14 3 3 protein beta/alpha antibody
    • 14 3 3 protein zeta/delta antibody
    • 14 3 3 zeta antibody
    • HS1 antibody
    • KCIP1 antibody
    • YWHAB antibody
    • YWHAZ antibody
    see all

Anti-14-3-3 beta + zeta antibody 画像

  • All lanes : Anti-14-3-3 beta + zeta antibody (ab79194) at 1/500 dilution

    Lane 1 : Extracts from 3T3 cells
    Lane 2 : Extracts from 3T3 cells with immunising peptide


    Predicted band size : 28 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.

Anti-14-3-3 beta + zeta antibody (ab79194) 使用論文

ab79194 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"