製品の概要

  • 製品名Anti-14-3-3 antibody
    14-3-3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 14-3-3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human, Xenopus laevis
  • 免疫原

    Synthetic peptide corresponding to amino acid residues from the C terminal region of 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH). Human.

  • ポジティブ・コントロール
    • rat brain hippocampus lysate
  • 特記事項


    Immunolabeling of the 14-3-3 protein band is completely blocked by pre-adsorption of the antibody with the C-terminal peptide that was used to generate the antibody.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 50% Glycerol, 0.1% BSA, 150mM Sodium chloride, 10mM HEPES. pH 7.5
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the C-terminal peptide used as antigen.
  • 一次抗体 備考Immunolabeling of the 14-3-3 protein band is completely blocked by pre-adsorption of the antibody with the C-terminal peptide that was used to generate the antibody.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab30579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 30 kDa.

ターゲット情報

  • 機能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
  • 配列類似性Belongs to the 14-3-3 family.
  • 翻訳後修飾The alpha, brain-specific form differs from the beta form in being phosphorylated (By similarity). Phosphorylated on Ser-60 by protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion.
    Isoform Short contains a N-acetylmethionine at position 1.
  • 細胞内局在Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 14 3 3 antibody
    • 14 3 3 protein beta antibody
    • 14 3 3 protein beta/alpha antibody
    • 14 3 3 protein zeta antibody
    • 14 3 3 zeta antibody
    • 14-3-3 protein beta/alpha antibody
    • 14-3-3 protein/cytosolic phospholipase A2 antibody
    • 1433B_HUMAN antibody
    • GW128 antibody
    • HS1 antibody
    • KCIP 1 antibody
    • KCIP-1 antibody
    • MGC111427 antibody
    • MGC126532 antibody
    • MGC138156 antibody
    • N-terminally processed antibody
    • Protein 1054 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide antibody
    • Tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide antibody
    • YWHAB antibody
    • YWHAD antibody
    • YWHAZ antibody
    see all

Anti-14-3-3 antibody 画像

  • Anti-14-3-3 antibody (ab30579) at 1/1000 dilution + rat brain hippocampus lysate

    Predicted band size : 30 kDa

Anti-14-3-3 antibody (ab30579) 使用論文

ab30579 has not yet been referenced specifically in any publications.

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Thank you for contacting us.

ab30579 is specific for the 14-3-3 protein zeta/delta isoform.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"