Anti-14-3-3 alpha + beta 抗体 (ab52995)

製品の概要

  • 製品名Anti-14-3-3 alpha + beta antibody
    14-3-3 alpha + beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to 14-3-3 alpha + beta
  • 特異性Broadly reactive with the ~29-32 kDa members of the 14-3-3 family of proteins. With the exception of a single, conserved amino acid change, this sequence is identical in the delta and zeta isoforms. Three and four conserved amino acid differences are found in the tau and gamma isoforms
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Rat, Cow, Human, Xenopus laevis, Caenorhabditis elegans
  • 免疫原

    Synthetic peptide derived from the N-terminus of the human 14-3-3 beta/alpha protein

  • ポジティブ・コントロール
    • HeLa cell lysate NIH3T3 cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab52995 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 30 kDa.
ELISA Use at an assay dependent concentration. The recommended dilution range 0.1-1ug/ml has only been tested in ELISA against the peptide (immunogen). More concentrated antibody might be needed for standard indirect ELISA.

ターゲット情報

  • 機能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
  • 配列類似性Belongs to the 14-3-3 family.
  • 翻訳後修飾The alpha, brain-specific form differs from the beta form in being phosphorylated.
    Isoform Short contains a N-acetylmethionine at position 1.
  • 細胞内局在Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 14 3 3 alpha antibody
    • 14 3 3 protein beta/alpha antibody
    • 14-3-3 protein beta/alpha antibody
    • 1433B_HUMAN antibody
    • Brain protein 14 3 3 beta isoform antibody
    • GW128 antibody
    • HS 1 antibody
    • KCIP-1 antibody
    • KCIP1 antibody
    • N-terminally processed antibody
    • Protein 1054 antibody
    • Protein kinase C inhibitor protein 1 antibody
    • YWHAA antibody
    • YWHAB antibody
    see all

Anti-14-3-3 alpha + beta antibody (ab52995) 使用論文

ab52995 has not yet been referenced specifically in any publications.

Product Wall

Application ELISA
Sample Human Tissue sections (cerebrospinal fluid)
Specification cerebrospinal fluid
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 25°C
Type Sandwich (Capture)
Username

Dr. M Schmitz

Verified customer

投稿 Aug 18 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"