(-)-MK 801 maleate, Non competitive NMDA antagonist (ab120028)
Key features and details
- Non competitive NMDA antagonist; less active enantiomer
- CAS Number: 77086-19-2
- Soluble in water to 25 mM, in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
(-)-MK 801 maleate, Non competitive NMDA antagonist -
製品の詳細
Non competitive NMDA antagonist; less active enantiomer -
生理活性の詳細
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CAS 番号
77086-19-2 -
構造式
製品の特性
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体系名
(5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate -
分子量
337.37 -
分子式
C16H15N.C4H4O4 -
PubChem 登録番号
16219612 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 25 mM, in DMSO to 100 mM and in ethanol to 50 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
O=C(O)/C=CC(=O)O.C[C@]42N[C@@H](Cc1ccccc12)c3ccccc34 -
由来
Synthetic
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研究分野
関連製品
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プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (2)
ab120028 は 2 報の論文で使用されています。
- Gallego-Delgado P et al. Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier. PLoS Biol 18:e3001008 (2020). PubMed: 33315860
- Fijal K et al. Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats. Psychopharmacology (Berl) 231:269-81 (2014). PubMed: 23954911